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Research Article Open Access
The study investigated the haemostatic effect of aqueous extract of Mushroom (Ganoderma lucidum) in rats using tail bleeding time and blood clotting time. Rats were divided into four groups of five rats (n=5) animals. Group I served as normal control, Group II received 200mg/kg b w, group III were given 400mg/kg b w while Group IV were administered with 800mg/kg b w of the extract intra-peritoneally for a period of ten days respectively. The findings of this study revealed a significantly decreased (P<0.05) bleeding time and clotting time at all doses 200, 400 and 800md/kg b w after 3rd day, with a non-significantly decreased (p>0.05) time observed after 6th and 10th day of administration plant extract respectively. In conclusion, this justifies the traditional use of Ganoderma Lucidum in stoppage of blood bleeding.
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Author(s): Tanko Y Eze E D Jimoh AYusuf K Mohammed K A Balarabe F andnbsp Mohammed A