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Research Article Open Access
Objective: This retrospective study aims to evaluate the influence of different variables incriminated as risk factors for pathological heart murmur (HM).
Methods: The study is conducted among 277 children aged between 0-14 years old referred to pediatric cardiology consultation upon a new finding of an isolated heart murmur. Therefore, they were divided into two groups (Case Group=pathological HM and Control group=Innocent HM) through the Doppler echocardiography diagnosis. A questionnaire was used later on to study all the socio-demographic factors and compare them between the two groups.
Results: Of 277 patients, pathological heart murmurs were found in 178 cases (64.26%). A statistically significant difference is found among seven variables: Consanguinity, Age<1 year, Low socio-economical status, Family history of congenital heart disease, North Region, Poly-malformation Syndrome, and presence of other clinical findings and abnormal symptoms associated to the murmur. Conclusions: These results show that genetic factors are recognized as the ultimate risk factor for congenital heart diseases (CHD), whereas environmental factors play a decreasing role through prevention policies adopted worldwide such as control of maternal diabetes, alcohol use during pregnancy, teratogenic drugs and rubella.
Heart Murmur, Congenital heart disease, Lebanon, Consanguinity, Heart Murmur, Congenital heart disease, Lebanon, Consanguinity