alexa Abstract | HER2 Status Examination of Biopsy Specimens from Gastric Mucosa

Journal of Gastroenterology and Digestive Diseases
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Letter to Editor Open Access

Abstract

ERBB2 (also called HER2) is a 185 kDa transmembrane tyrosine kinase receptor. Overexpression as a result of HER2 gene amplification on chromosome 17q11.2-q12 has been observed in solid tumors including gastric and breast cancers1. HER2 is amplified in 7%-20% of gastric cancers2-5. Overexpressed HER2 is a therapeutic target of Trastuzumab, a humanized monoclonal antibody that binds to the extracellular juxtamembrane domain of ERBB2 and inhibits the proliferation and survival of HER2-overexpressing cancer cells6 (Figure 1).

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Ooi Akishi

Keywords

Erbb2, Gastric cancer, Mucosal biopsy, IHC, FISH, Barrett’s Oesophagus, Peptic ulcers, Crohn’s Disease, Diverticulitis, Hernia, Dumping Syndrome, Gall stones, Hemorrhoids, Diarrhoea, Pancreatitis, Bloating & wind, Coeliac disease, Constipation, Faecal incontinence, Heartburn, Helicobacter Pylori, Indigestion, Liver cancer, Gastric Cancer

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords