alexa Abstract | Hypoglycemic and hypolipidemic effects of flavonoids from tatary buckwheat in type 2 diabetic rats.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Present study was designed to evaluate hypoglycemic and hypolipidemic effects of flavonoids from tatary buckwheat (TBF) in type 2 diabetic rats induced by combination of high-fat diet and streptozotocin injection. After induction of type 2 diabetes, diabetic rats were randomly divided into five groups: diabetic control group, low-dose TBF treated group, middle-dose TBF treated group, high -dose TBF treated group, and glibenclamide treated group, with normal rats used as the control group. After treatment for 28 days, body weight, fasting blood glucose (FBG), serum insulin, total cholesterol (TC), triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C) levels were measured and oral glucose toler ance test (OGTT) was performed. The results showed that TBF significantly decreased FBG and serum insulin levels, increased body weights and improved glucose intolerance in diabetic rats. Furthermore, it decreased TC, TG, and LDL-C levels and increased HDL-C levels in these rats. These evidences indicated that TBF possesses hypoglycemic and hypolipidemic effects in type 2 diabetic rats and suggested that TBF has the potential to be a candidate for investigation as an anti-diabetic agent in humans.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Jing Li Fayong Gong Fenglin Li

Keywords

2

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords