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Research Article Open Access
The present study was undertaken to examine the inhibitory effect of the Bulbs part of Onion (Allium cepa.L) on Lead acetate induced hepatotoxicity in Liver. Enhanced synthesis of Total cholesterol and decreased synthesis of HDL cholesterol were observed in the liver of Lead acetate poisoned rats. Administration of the Paste of Allium cepa 500 mg/kg body weight effectively suppressed the synthesis of cholesterol in the liver, thus controlling the effect of Lead acetate. The results suggest that Allium cepa may exert a protection effect by inhibiting the synthesis of cholesterol and the vitamins induced by Lead acetate.
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Author(s): P Vinoth Kumar A Amala Pricy Ch Sudheer kumar V Vimal and V Veera Thamarai Selvi
Lead acetate intoxication, Onion (Allium cepa.L), Cholesterol, Lipoprotein.