alexa Abstract | Immunoglobulin levels and nutritional status of children with Down syndrome

Current Pediatric Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


The present study was conducted to determine the levels of immunoglobulins in Down syndrome and correlate them with nutritional status. There were 30 children with Karyotypically confirmed Down syndrome . Anthropometric measurements were recorded using standard techniques to assess nutritional status. Serum IgG, IgA and IgM concentrations were determined using automated nephelometer. The immunoglobulin levels were correlated with nutritional status of children with Down syndrome. Out of 30 children with Down syndrome, 13 were males and 17 females. Their ages ranged from 1.5 to 9 years. Seventeen children were normally nourished whereas 6 children had grade I malnutrition, 7 cases grade II and III malnutrition. The levels of IgG ( 13.32± 4.25 to 10.73 ± 2.64 g/l ) and IgA ( 1.345 ± 0.16 to 1.079 ± 0.42 g/l ) decreased with increasing grades of malnutrition whereas the levels of IgM ( 1.084 ± 0.413 to 1.256 ± 0.22 g/l ) increased with increasing grades of malnutrition. In the present study, the serum immunoglobulins showed statistically insignificant alterations with various grades of malnutrition.

To read the full article Peer-reviewed Article PDF image

Author(s): Deepa C Parkash Chand Vishnu Bhat B Negi VS Ramachandra Rao K


Down syndrome, Impaired immunity, Immunoglobulins, Respiratory tract infections, Malnutrition

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version