alexa Abstract | Improved Diffusion Rate with Triple Well Potential for Stem Cell Image Segmentation

Journal of Biomedical Sciences
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Research Article Open Access

Abstract

Segmentation of stem cells is a challenging process in image processing where level set method is used extensively. This level set criterion with re-initialisation process reduces its wider range of application. Thus re-initialisation is eradicated by a method called distance regularisation in which the signed distance property is maintained near the zero level set via forward and backward (FAB) diffusion effect. A potential function is habituated to sustain the desired shape of the level set function. The initial potential function used in distance regularisation is single-well potential technique that causes excess backward diffusion and oscillation in LSF, so it is succeeded by double-well potential. But this double well technique losses the capability to conserve the regularity at some points. This problem is eliminated by a new novel method called improved diffusion rate with triple-well potential. The proposed diffusion rate can maintain the signed distance property of the level set function (LSF) and overcome the side effect of double-well potential with reduced number of iterations.

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Author(s): R Nathiya G Sivaradje

Keywords

Level set method (LSM), Image segmentation, Re-Initialization, Forward and backward diffusion (FAB), Single well potential,Double well potential, Triple well potential, Biomedical science, Genetics, Cognitive and neurosciences

 
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