alexa Abstract | IN VITRO ANTIOXIDANT AND ANTHELMINTIC ACTIVITY OF EXTRACTS OF JASMINUM ARBORESCENS ROXB

International Journal of Drug Development and Research
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Abstract

The present study was carried out to study in vitro antioxidant and anthelmintic activity of ethanol, chloroform and petroleum ether extracts of leaves of Jasminum arborescens Roxb (Oleaceae). Different concentrations of solvent extracts were subjected to antioxidant activity by DPPH free radical scavenging and Fe+3 reducing power assays. A marked dose dependent antioxidant activity was observed in the trials. Antioxidant activity was higher in ethanol extract followed by chloroform and petroleum ether extract. Anthelmintic assay was performed on adult Indian earthworm Pheretima pasthuma. The time taken for paralysis and death of worms was found lesser in case of ethanol extract followed by chloroform and petroleum ether extract. The results of the study indicate the antioxidant and anthelmintic potential of solvent extracts. Further studies on isolation of constituents and antioxidant and anthelmintic activity in vivo are to be carried out.

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Author(s): BHAGATH K PRASHITH KEKUDA TR RAGHAVENDRA HL SWARNALATHA SP PREETHI HR SURABHI K S

Keywords

Jasminum arborescens Roxb., Soxhlet extraction, DPPH free radical scavenging assay, Fe+3 reducing power assay, Pheretima pasthuma

 
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