alexa Abstract | Incidence and Etiology of Acute Kidney Injury in Children Admitted to PICU using PRIFLE Criteria

Current Pediatric Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Introduction: Acute Kidney Injury (AKI) is associated with severe morbidity and mortality. Lack of consensus definition has been major limitation in improving outcomes. Acute Dialysis Quality Initiative Group (ADQI) group proposed RIFLE (Risk, Injury, Failure, Loss of function, End stage renal disease) criteria, criteria for defining AKI, later modified in children as pRIFLE (pediatric RIFLE). This study tries to address the need of limited data on pediatric AKI.
Methodology: A prospective study conducted in between December 2013 to May 2015. Serum creatinine level was estimated on all patients on admission and alternate days till discharge from Pediatric Intensive Care Unit (PICU). Urine output was recorded. Estimated Creatinine- Clearance (eCrCL) was calculated using Schwartz formula. AKI diagnosis and staging was based on pRIFLE (pediatric RIFLE) criteria. Either eCrCl or urine output criteria were used to diagnose and stage AKI, using criterion that leads to higher stage. Maximal stage that the patient progressed during the stay in PICU was assigned the stage for that case. Data was compiled using SPSS software.
Results: Of total 697 cases, 680 cases met inclusion criteria. Incidence of AKI was 178 (26.1%). Stage ‘Risk (R)’, ‘Injury (I)’ and ‘Failure (F)’ constituted 60.7% (108), 28.6% (51) and 10.6% (19) respectively. Maximum AKI occurred in < 1 year (28.1%) (p=0.003). Urine output and creatinine criteria matching were there in 77%. Infections were commonest etiology. Amongst infections dengue (30%) was most common, followed by sepsis (21.9%) and then pneumonia (17.9%). Hypotension, nephrotoxic drugs, sepsis, need for mechanical ventilation were significant (p<0.001) risk factors for AKI. Prerenal causes constituted 68% and renal 32%.
Conclusion: Incidence of AKI is high among critically ill children. pRIFLE staging system that provides early identification and stratification of AKI. Infections are leading etiology of AKI in children.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Srinivasa S Reshmavathi V

Keywords

AKI, pRIFLE, PICU, Children

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords