alexa Abstract | Mercurimetric Titration of Some Beta Lactam Antibiotics in Bulk and Pharmaceutical Products

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


A simple, sensitive and rapid method is described for the determination of some derivatives of beta lactam antibitics in bulk drug and in tablet dosage forms. In this method, ampicillin and amoxicillin are first degraded in 1 M NaOH medium for 20 min, acidified with nitric acid then titrated volumetrically with mercuric ions in the presence of few drops of diphenlycarbazone. The method is applicable over 0.3-2 μg/ml range of antibiotics and the stoichiometric reaction between antibiotic and mercury is found to be 2:3, respectively. Intra-day and inter-day precision and accuracy for the developed methods were evaluated. The method is successfully applied to the assay of antibiotics in capsule and injection formulations and the results were statistically compared with those of a reference method. No interference was observed from common capsule excipients.

To read the full article Peer-reviewed Article PDF image

Author(s): Hamad M I Hasan Ibrahim H Habib and Suad K Omar

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version