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Research Paper Open Access
An attempt was made to provide cheaper, indigenous, directly compressible lactose by thermal modification of lactose I.P. The modified lactose (Thermally modified lactose, TML) was characterised for physico-chemical properties and flow behaviour and the results compared with those of Marketed directly compressible lactose (MDL). The direct compressibility of TML and MDL was also evaluated by compression on a rotary tablet compression machine. Results indicated TML to be a promising directly compressible excipient which can replace imported directly compressible lactose.
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Author(s): A B Rao A N Misra