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Context Pancreatic heterotopia in itself is rare in the colon and to the best of our knowledge a neoplasm arising in aheterotopic tissue in the colon has not been reported. We herein report a pancreatic cystic neoplasm arising fromheterotopic pancreatic tissue in colon. Case report A 44-year-old lady presented with a history of lower abdominal colic,associated with mucoid loose stools 10-15 times/day. Fecal occult blood was positive on two occasions. On examination, avague mass was palpable in the left upper quadrant of abdomen. Colonoscopy showed a polypoid growth at the splenicflexure of colon, which on biopsy was reported to be an inflammatory polyp. She underwent a laparoscopic converted toopen left hemicolectomy. Post-operatively she developed a intra-abdominal collection which formed a controlled pancreaticfistula after percutaneous drainage. Histopathology revealed pancreatic heterotopia with pancreatic mucinous cysticneoplasm. Conclusion Despite advances in patient care, preoperative diagnosis of heterotopic pancreas is difficult.