alexa Abstract | Multi-Modality Therapy for Primary Squamous Cell Carcinoma of the Ampulla of Vater - Report of a Rare Case with Literature Review

JOP. Journal of the Pancreas
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report Open Access


Background Primary squamous cell carcinoma of the ampulla of Vater is a rare tumor, and the treatment and prognosis of which is not well known because of limited number of reported cases in the literature. Here, we report the case of primary squamous cell carcinoma of the ampulla of Vater, treated with multimodality therapy (surgery and adjuvant chemotherapy), and have a longer survival than the reported cases in the literature. Case presentation A Sixty-five-year-old woman presented with painless progressive jaundice and generalized itching. The clinical presentation, radiographic and endoscopic investigations strongly suggest periampullary carcinoma. We performed Pylorus-preserving pancreaticoduodenectomy with curative intent. Histopathological examination and immunohistochemistry analysis revealed primary squamous cell carcinoma of ampulla of vater. The postoperative course was uneventful. The patient received adjuvant chemotherapy, and patient is on follow up with no tumor recurrence, and having a good quality of life for last 1 year after multimodality therapy. Conclusion Primary squamous cell carcinoma of the ampulla of Vater is a rare histological type. The literature review revealed the poor prognosis of all the reported cases of primary squamous cell carcinoma of the ampulla of Vater. The optimal treatment and prognosis is unclear. To the best of our knowledge, this is the first report of primary squamous cell carcinoma of the ampulla of Vater that was treated with multimodality therapy. With our experience, we suggest that multimodality treatment should be the mainstay therapy for primary squamous cell carcinoma of the ampulla of Vater. However, more number of studies on clinico-pathological findings and treatment modality are required to determine appropriate treatment strategy and prognosis of this tumor.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Sudarshan Reddy Sadaf Ali Bangri K Dinesh Ajaz A Wani Sharan Kumar N Khalid Basheer B Sourabh J


Ampulla of Vater, Carcinoma, Pancreas, Cell Carcinoma

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version