alexa Abstract | New, Simple and Sensitive Voltammetric Procedure for Determination of Paracetamol in Pharmaceutical Formulations

Insights in Analytical Electrochemistry
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

A new, simple and sensitive adsorptive stripping voltammetric procedure for determination of paracetamol at a lead film glassy carbon electrode modified with Nafion film (Nafion/PbF/GCE) in pharmaceutical formulations was described. Deposition of lead film on a glassy carbon electrode from 0.1 mol L-1 HNO3 at the potential of -1.4 V was performed. The Nafion film coating was carried out by applying a 0.5 µL drop of 1% (w/v) Nafion solution onto the lead film electrode surface. At the potential of -1.45 V for 60 s paracetamol was accumulated by adsorption on the electrode from 0.1 mol L-1 H2SO4. Experimental results indicate excellent linear correlation between the paracetamol peak current and its concentration in the range from 5 × 10-7 to 1 × 10-2 mol L-1 with accumulation time equal to 60 s. The detection and quantification limits were 1.72 × 10-7 mol L-1 and 5.97 × 10-7 mol L-1, respectively. The elaborated procedure was successfully applied for determination of paracetamol in commercially available pharmaceutical formulations.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Ilona Sadok and Katarzyna TyszczukRotko

Keywords

Nafion Covered Lead Film Glassy Carbon Electrode, Adsorptive Stripping Determination, Paracetamol Determination, Pharmaceutical Analysis, Voltammetry, Coulometry, Biosensors, Medicine, Pharmacy, Environmental Monitoring

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords