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Short Communication Open Access
Three simple and sensitive spectrophotometric methods have been described for the determination of cisapride, based on the coupling of the diazotised drug with the reagents such as chromotrophic acid (method A), phloroglucinol (method B) and N- (1-naphthyl) ethylene diamine dihydrochloride, NED (method C) to give coloured products having maximum absorbances at 530nm, 450nm and 540nm, respectively. These methods are extended to the analysis of pharmaceutical formulations and results compared with the UV reference method.
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Author(s): C S P Sastry Y Srinivas P V Subba Rao