alexa Abstract | New spectrophotometric methods for the determination of racecadotril in bulk drug and capsules

Indian Journal of Pharmaceutical Sciences
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Abstract

Two simple and sensitive spectrophotometric methods (A and B) for the determination of racecadotril in bulk drugs and pharmaceutical formulations are described. In method A, methanol was used as solvent and shows absorption maximum at 231 nm. In method B, the solvent used was acetonitrile:water in the ratio of 1:3 and shows absorption maximum at 232 nm. The Beer's law range for method A is 25-100 mg/ml and 20-80 mg/ml for method B. When capsules dosage forms were analyzed, the results obtained by the proposed methods are in good agreement with the labeled amounts and the results were validated statistically.

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Author(s): T Vetrichelvan S Prabakaran

 
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