alexa Abstract | New Spectrophotometric Methods For The Determination Of Salmeterol Xinafoate

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access

Abstract

Two simple and sensitive spectrophotometric methods (A and B) in the visible region have been developed for the determination of salmeterol xinafoate (SX) in bulk and in dosage forms. Method A is based on the reaction of SX with hydrochloric acid and sodium nitrite under alkaline conditions to form a stable yellow colored chromogen with absorption maximum of 430 nm and method B is based on the reaction of SX with ferric alum reagent to form a stable blue colored chromogen with the absorption maximum of 620 nm. The color obeyed Beer's law in the concentration range of 0-32 μg/ml for method A and 0-200 μg/ml for method B respectively. When pharmaceutical preparations (Laboratory prepared tablets) were analysed, the results obtained by the proposed methods are in good agreement with the labelled amounts and are comparable with the results obtained using a UV spectrophotometric method. Recovery in both the methods is 98-101%.

To read the full article Peer-reviewed Article PDF image

Author(s): K P R Chowdary G Devala Rao

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords