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Original Articles Open Access
8-Chloro-3- cyano – 2 – methylthio - 4-oxo - 4H – pyrimido [2,1-b][1,3]benzothiazole (3) on reaction in presence of dimethyl formamide and catalytic amount of anhydrous potassium with hydrazine hydrate / aryl hydrazine / heteryl hydrazine afforded 3-amino-8-chloro-4-oxo-(2H) / aryl/ heteryl-pyrazolo [3’,4’:4,5] pyrimido [2,1-b] [1,3] benzothiazoles (4a-i) in good yield. These newly synthesized compounds were evaluated for antibacterial activity.
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Author(s): Vijay N Bhosale Sambhaji PVartaleVinayak K Deshmukh and Sharad V Kuberkar
Ethyl-2-cyano-3 3-bismethylthioacrylate, hydrazine hydrate,aryl and heteryl hydrazines