700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ ReadersThis Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Original Articles Open Access
New synthetic methodology for the synthesis of dibenzo[b,e][1,4]diazepines, a key intermediates in the manufacturing of Clozapine which is indicated for use in therapy as dopamine receptor antagonist, Antipsychotic drug . Synthesis of 2-(4-chloro-2-nitrophenylamino) benzoic acid methyl ester by simple rearrangement of2-[[2- (4-chloro-2-nitrophenoxy)acetyl]amino]benzoic acid methyl ester. The present work describes a novel, cost-effective and easily scalable process of dibenzo[b,e][1,4]diazepines.
To read the full article Peer-reviewed Article PDF
Author(s): Nitin A Shimpi and Rajesh B Dhake
Clozapine, Dopamine receptor antagonist, dibenzo[b,e][1,4]diazepines, dibenzo azepines