alexa Abstract | One-pot synthesis of substituted dihydro-2-oxypyrroles catalyzed by (S)-camphorsulfonic acid

Journal of Chemical and Pharmaceutical Research
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Abstract

A mild and efficient synthesis of substituted dihydro-2-oxypyrroles has been developed for the one-pot, four-component condensation reaction of dialkylacetylene dicarboxylate, amines and formaldehyde using (S)-camphorsulfonic acid as the catalyst at room temperature. The use of (S)-Camphorsulfonic acid makes this process quite simple, more convenient and environmentally friendly

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Author(s): Xiaojuan Yang

Keywords

(S)-Camphorsulfonic acid, Dialkylacetylene dicarboxylate, Multicomponent reactions, camphorsulfonic

 
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