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The aqueous leaf extract, after six weeks administration to the animals showed no difference in the morphology of the heart, liver, kidney and intestinal tissues of the treated and un-treated animals. Body weights of both the treated and untreated animals rose progressively as the period increased. The plant extract produced no significant changes in packed cell volume (PCV), white blood cell (WBC) and platelet counts. This study suggests that the plant extract is non-hazardous, even when taken for some time.
Toxicity,, Vernonia amygdalina, haematological parameters, biochemical parameters, histopathology