alexa Abstract | Oxytocin potentiates carbachol-induced lacrimation in female wistar rats

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Oxytocin is a posterior pituitary hormone with important physiological functions. Oxytocin has traditionally important biological functions in regulating the uterine smooth muscle activity and milk ejection during lactation. This study was conducted on albino Wistar female rats to evaluate the effect of oxytocin on carbachol induced lacrimation. Groups of animals (n=7) were injected with oxytocin or its agonist [Thr4, Gly7]oxytocin 25 minutes before carbachol injection (0.6mg/kg i.p). In groups of animals pretreated with saline, there was 31.4 μl increase in carbachol induced tear secretions which was further increased to 65.2 μl and 47.3 μl, respectively after oxytocin and [Thr4, Gly7]oxytocin pretreatment. These results suggest a novel facilitatory role of oxytocin in carbachol induced lacrimation.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Manoj G Tyagi


Oxytocin, carbachol, lacrimation, cholinergic

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version