alexa Abstract | Phagocytosis: A marker of decreased immune response in radia-tion treated oral cancers

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Mucositis, a serious complication in head and neck cancer patients could be the cause for, or consequence of decreased activity of granulocytes in oral mucosal secretions. This in turn may be attributed to poor body immunity in such patients. In the present study, the phagocytic activity of peripheral blood granulocytes was evaluated to understand its role in mucositis,and concurrent immunosuppression. Granulocytes from 15 oral cancer patients were collected and tested for phagocytic activity, by assessing the percent phagocytosis and phagocytic index of the granulocytes towards candida albicans before and after radiotherapy. The results were compared with normal healthy subjects(n=15).Percent phagocytosis decreased significantly (p<0.001) in baseline samples compared to controls as well as in post treated samples when compared to baseline samples(p<0.05). Phagocytic index decreased significantly in the post treated samples as against the baseline samples (p<0.05) although the changes were non significant between controls and patients. This decrease in phagocytic activity was coupled with progressive mucositis , which suggests that the decreased functional activity of the peripheral granulocytes could be the underlying cause for the altered immune response in cancer patients subjected to radiation.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Reshma K Bharathi B Rao AV Dinesh M Vasudevan DM

Keywords

Oral cancer, radiotherapy, mucositis, phagocytosis

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthca[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords