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Research Paper Open Access
The pharmacodynamic effects of Cedrus deodara wood essential oil were investigated in mice and rats. The oil was found to possess significant anti-inflammatory activity in carrageenin-induced oedema in rats. It was devoid of analgesic, sedative and motor incoordinating activities in mice. However, it caused a significant increase in pentobarbitone-induced hypnosis which may be due to inhibition of drug metabolising enzymes.
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Author(s): S K Tandan S Chandra S Gupta J Lal