alexa Abstract | Pharmacognostical and phytochemical evaluation of Angelica archangelica Linn.

International Journal of Drug Development and Research
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Abstract

Ethnopharmacological relevance: Angelica archangelica Linn. is a herb distributed in tropical and subtropical regions of the world. Angelica is largely used in grocery trade as well as for medicine. The herb is traditionally used for the treatment of leukoderma, nervous headaches, fever, skin rashes, wounds, rheumatism, toothaches, gastric ulcers, anorexia, migraine, bronchitis, chronic fatigue, menstrual and obstetric complaints and for dental preparation. Aim of the study: Evaluation of preliminary Pharmacognostical and phytochemical parameters of Angelica archangelica Linn. Material and methods: The whole plant material was subjected to successive soxhlet extraction with petroleum ether (40-600C), chloroform, ethyl acetate, methanol and finally decocted with water to get respective extracts. Fluorescence characters of powdered material were analysed under ultraviolet light and ordinary light. Different physicochemical parameters such as ash value, extractive value, foaming index, pH values, loss on drying and determination foreign matter were carried out as per WHO guidelines. The total fat, flavonoid and saponin contents were also determined. Results and discussions: Macroscopical studies revealed the authentication of plant drug. Physicochemical parameters helped to standardize the plant material while Preliminary qualitative chemical test of different extracts showed the presence of Glycosides, Carbohydrates, Phytosterols/triterpenoids, Saponins, Fixed oils & Fats and phenols/tannins. Quantification of total flavonoids, saponins and fat contents was also carried out. Conclusion: Results shall pave a way in the standardization of the drug

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Author(s): Dinesh Kumar Zulfiqar Ali Bhat Vijender Kumar I A Chashoo N A Khan M Y Shah

Keywords

Angelica Archangelica Linn., Physicochemical parameters, Phytochemical analysis, successive solvent extraction

 
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