700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ ReadersThis Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Research Paper Open Access
Fifteen different isatin-[N-(2-alkylbenzoxazole-5-carbonyl)] hydrazones prepared earlier were screened for analgesic, antidepressant and H1-antihistaminic activities, and also for their effect on pentobarbi-tone-induced narcosis, by standard methods. Results revealed that three compounds h, n and e possessing a methyl substituent at 7-position of the benzoxazole system could exhibit good analgesic activity, in relation to standard. Five of the test compounds, h, g, j. n and i were to potentiate the pentobarbitone-induced narcosis more powerfully than imipramine HCI. The antidepressant and H1-antihistaminic activities of these compounds were not comparable to those of the standards imipramine HCI and diphenhydramine. HCI, employed in the investigation. Out of all, only compound k was found to exhibit all the tested activities, though to varied extents.
To read the full article Peer-reviewed Article PDF
Author(s): M Saragapani V M Reddy