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Research Paper Open Access
Three extracts of Hibiscus rosasinensis Linn. have been prepared and evaluated for hypotensive activity. Hydroalcoholic extract was found to exhibit prominent activity when compared to the reference standard minoxidil. In an attempt to isolate the active constituents responsible for this activity from hydroalcoholic extract, five new phytoconstituents were isolated and their structures were elucidated from spectral evidence (IR, NMR and Mass). Hypotensive activity of these isolated compounds was also studied.