alexa Abstract | Phytochemical Screening And Hepatoprotective Properties Of The Aqueous Root Bark Extract Of Sarcocephalus latifolius (Smith) Bruce (African Peach)

Archives of Clinical Microbiology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Objective: The hepatoprotective properties of the aqueous extract of Sarcocephalus (S). latifolius (Smith) Bruce was studied by investigating its effect on some serum biochemicalparameters in rats treated with Carbon tetrachloride (CCl4).

Methods: Twenty Wister albino rats weighing 200-230g were divided into five groups of five rats each (Group A, B, C, D and E) by random selection.Rats in groups B, C and D wereorally administered 100mg/kg, 200mg/kg and 300mg/kg body weight aqueous extracts daily for 20 days, while group A (control) was injected with 5ml/kg body weight normalsaline for the same period. The animals in groups B, C, D and E were injected intraperitoneally with 3mg/kg body weight of CCl4; on the last day and observed for 24hours afterwhich they were sacrificed by decapitation and blood collected for biochemical and haematological analysis.

Result: Phytochemical analysis of the aqueous extract showed the presence of flavonoids, alkaloids, carbohydrates, tannins and saponins. Alanine transaminase (ALT), Aspartatetransaminase (AST), total and conjugated bilirubin levels were significantly decreased (P<0.05) across all the groups treated with extract and the toxin (CCl4). The decrease wasdose dependent.Conclusions: The decrease observed in the biochemical parameters, suggest that the aqueous extract of S. latifolius possess hepatoprotective properties.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): H B Yesufu P U Bassi I Z Khan F I Abdulrahaman G T Mohammed

Keywords

Mycobacterial Diseases, Bacterial Infection

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords