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Original Articles Open Access
This review summarizes the in vitro and in vivo medicinal chemistry investigations for piperazine and morpholine analogues. Piperazine and morpholine nucleus show a broad spectrum of pharmaceutical applications, thus, in recent years, scientists has developed various new methods for the synthesis of their derivatives. This review shows current tendency in the piperazine and morpholine analogues synthesis and reveals their potent pharmacophoric activities.
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Author(s): Mohammed AlGhorbani Bushra Begum A Zabiulla Mamatha S Vand Shaukath Ara Khanum
Piperazine, morpholine, synthesis, pharmaceutical applications