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Review Article Open Access
Poloxamers/Pluronic block copolymers are recognized pharmaceutical excipients listed in US and British Pharmacopeias. Because of the thermo-reversible gelation property and low toxicity they are widely used in a variety of pharmaceutical formulations including delivery of low molecular weight drugs and high molecular weight polypeptides. This review describes recent reports of applications of poloxamers in drug delivery, gene therapy, tissue engineering and in neuroprotection.
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Author(s): D S Singhare Shagufta Khan P G Yeole