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Original Articles Open Access
Polyethylene glycol (PEG-400) was found to be an effective reaction medium for the one-pot synthesis of 4-(1-aryl- 2-nitroethyl)-3-methyl-1H-pyrazol-5-ol derivatives in good yields under mild reaction conditions. The use of PEG- 400 makes this method low cost, recyclable, and eco-friendly.
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Author(s): Ramakoteswara Rao Chinta Vijay Kumar Tulam Prathama S Mainkar and P K Dubey
Michael addition, Catalyst-free conditions, Pyrazole, Hetero cyclic, styrene, Polyethylene glycol, catalyst