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Introduction: Coronary artery disease features among the top three causes of premature deaths in both men and women in Malaysia.
Aim and Objectives: The objectives of the study are to determine the proportion of premature coronary artery disease (CAD), its angiographic findings and risk factors among patients with angiographically proven CAD in a tertiary center in Malaysia.
Methods / Study Designs: This was a retrospective study involving three hundred and thirty five medical records of patients undergoing coronary angiogram from 2002 until 2004 were reviewed. The socio-demographic, associated risk factors and angiographic findings were recorded.
Findings: The result of the study showed a total of 165 cases were diagnosed to have CAD based on coronary angiogram. The proportion of premature CAD was 55% (n=92). The risk factors associated with premature CAD were family history of heart disease (p<0.05) and low High Density Lipoprotein level (HDL) (p<0.05).There was a high prevalence of Premature CAD among angiographically proven CAD in this study. Family history of heart disease and low HDL level were associated with premature coronary artery disease.
Conclusion: Early cardiovascular screening in family member of patient with heart disease is important for prevention of coronary artery disease in young adult.
coronary artery disease, premature CAD, coronary angiogram, premature heart disease