alexa Abstract | Preparation And Characterization Of Agglomerates Of Flurbiprofen By Spherical Crystallization Technique

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access


Flurbiprofen is an analgesic and antiinflammatory drug with poor water solubility and compressibility. Flurbiprofen conventional drug crystals were converted into spherical crystal agglomerates via the spherical crystallization technique using acetone-water-hexane solvent system. The various parameters optimized were type, amount and mode of addition of bridging liquid, temperature, and agitation speed to get maximum amount of spherical crystals. These were characterized for micromeritic properties (particle size and shape, flowability), packability (bulk density), wettability (contact angle) and compressibility. It was revealed from the study that spherical agglomerates exhibited improved flowability, wettability and compaction behaviour.

To read the full article Peer-reviewed Article PDF image

Author(s): MK Chourasia Nitin K Jain S Jain NK Jain SK Jain

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version