alexa Abstract | Preparation And Evaluation Of Muco-Adhesive Buccal Tablets Of Hydralazine Hydrochloride

Indian Journal of Pharmaceutical Sciences
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Multilayered muco-adhesive buccal tablets of hydralazine hydrochloride were developed using polymers, which as Carbopol- 934 and carboxymethylcellulose. Release enhancers such as citric acid, D-mannitol and PEG-4000 and techniques like lyophilization were utilized for optimization of the tablet core. A Millipore membrane filter (0.22mm) was used satisfactorily to replace animal membrane for drug permeation studies across the membrane.

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Author(s): Dinsheet S P Agarwal Alka Ahuja

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