alexa Abstract | Prevalence of left ventricular hypertrophy in end stage renal disease

International Journal of Collaborative Research on Internal Medicine & Public Health
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Introduction: Cardiovascular disease (CVD) is still the major cause of death in patients with end stage chronic kidney disease (ES-CKD), with a mortality rate approximately 10 to 30 times greater than that of the general population. Advanced cardiomyopathy is caused by left ventricular hypertrophy (LVH) in patients with end stage kidney disease.

Objective: The objective of the study is to determine the prevalence of LVH in end stage renal disease (ESRD) patients.

Methods: This was a cross sectional study conducted at Department of Nephrology, Kulsom Bi Valika Social Security Site Hospital, Karachi. The sampling technique was non probability convenient sampling and the sample size was calculated by using the WHO software. Patients included in this study were of known cases of end stage renal disease. Patients excluded from the study were of ischemic heart and valvular heart disease. Linear Regression Analysis was conducted and R value was computed.

Results: R2 value indicates 83% of the dependent variable of left ventricular mass can be explained by the independent variables of Systolic Blood Pressure and Diastolic Blood Pressure. Scatter plot between creatinine and hemoglobin showed negative correlation. A rise in serum level of creatinine showed a decreased serum level of hemoglobin. Scatter plot between left ventricular hypertrophy and creatinine showed positive correlation. An increase in left ventricular mass showed an increase serum creatinine level.

Study Limitation: Few biochemical parameters were conducted.

Conclusion: Left Ventricular Hypertrophy is frequent in End Stage Renal Disease.

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Author(s): Nahida Baigam Musleh Uddin Kalar Saeeda Fouzia Qasim Arfa Saeed Harris Alvi


Left Ventricular Hypertrophy (LVH), End Stage Renal Disease (ESRD), anemia, renal function, creatinine.

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