alexa Abstract | Protection of Deliquescence of Sodium Valproate by Hydrotalcite Using Different Synthetic Routes

Journal of Pharmaceutical Microbiology
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Protection of deliquescence of sodium valproate from humidity was accomplished successfully by a solid-solid reaction with hydrotalcite. The level of protection was comparable to that obtained when the compound is synthesized by ion-exchange reaction in aqueous solution. The merit of the solid-solid reaction is enormous because the procedure consists of simply grinding the solid sodium valproate with hydrotalcite for 5 min.

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Author(s): Hirokazu Nakayama and Aki Hayashi


Sodium valproate, Deliquescence, Pharmaceuticals, Hygroscopicity, Sodium valproate, Deliquescence, Pharmaceuticals, Hygroscopicity

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