alexa Abstract | Protective effect of ginger oil on aspirin and pylorus ligation-induced gastric ulcer model in rats

Indian Journal of Pharmaceutical Sciences
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Abstract

The present investigation was performed in aspirin and pylorus ligation-induced ulcer model in Wistar rats, in which ability of ginger oil to provide gastric protection was studied at two different doses, 0.5 and 1 g/kg po. Gastric protection was evaluated by measuring the ulcer index, serum λ- GTP levels, total acidity of gastric juice and gastric wall mucus thickness. The results obtained in the present study indicated that ginger oil has a protective action against gastric ulcers induced by aspirin plus pylorus ligation in Wistar rats.

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Author(s): M Khushtar V Kumar K Javed Uma Bhandari

Keywords

Gastric ulcer, ginger oil, λ-GTP, aspirin and pyloric ligation

 
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