alexa Abstract | Quantitative and qualitative coding of Lactate dehydrogenase isoenzymes and their genes: Evolutionary implication in genus Channa (Channidae: Channiformes)

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Lactate dehydrogenase (LDH: is a tetrameric enzyme participates in carbohydrate metabolism by catalyzing the oxidation of lactate and reduction of pyruvate. The random tetramerization of LDH-A and -B subunits leads to the formation of five tetramers: LDH-B4, LDH-A1B3, LDH-A2B2, LDH-A3B1 and LDH-A4. Due to the biochemical and evolution-ary significance of LDH isoenzyme characters or LDH genes, efforts are made here to pro-pose a numerical coding method of quantifying the isoenzyme activities and demonstrate the presence of LDH loci or the changing levels of isoenzymes in different tissues of selected air-breathing teleosts Channa punctata, C. gachua and C. striatus. Polyacrylamide gel electro-phoretic (PAGE) profiles of LDH isoenzymes were utilized and software analysis of gel scans was performed. Our results show a great variation in the quantitative as well as quali-tative presence of isoenzymes or their genes among the selected freshwater congeneric spe-cies. Based on the obtained results, adaptive strategies of Channa species are discussed in re-lation to their evolutionary set up.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Riaz Ahmad


LDH isoenzymes, differential gene expression, steady-state patterns, polyacrylamide gel electro-phoresis, Channa, evolutionary genetics, #

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us