alexa Abstract | Quest for anthelmintic agents part IV some analouges of bephenium and tetramisole

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


Some analouges of bephenium (1) and tetramisole (2) were prepared for anthelminitic screening. 2-Benzimidazolyl (3), (N-benzyl-8-quinoliniumoxy) ethyl-N-benzyl (4), isoindolinium (5), 1,2,3,4-tetrahydroisoquinolinium (6) and 3-azabicylo [3.2.2] nonanium (7) analogues of (1) and tetramisole analouges, 6-(2-benzthiazolyl)-2,3-dihydroimidazo [2,1-b] thiazole (10) and 5-(2-benzthiazolyl)-2,3-dihydrothiazolo [2,1-a] imidazole (12) were synthesised and found to be inactive against N. americanus infection in hamster.

Author(s): K Nagarajan VR Rao AN Goud

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