alexa Abstract | Replacement of Intervertebral disc in Spine by Poly (ethylene glycol) - diacrylate (PEGDA) material through Stereolithography.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Cervical and lumbar disc replacements are being performed in the modern world with increasing frequency. The intervertebral discs are fibrocartilaginous cushions serving as the spine's shock absorbing system, which guard the vertebrae, brain, and other structures (i.e. nerves). The discs permit some vertebral motion: extension and flexion. Single disc movement is very limited – however considerable motion is possible when several discs combine forces. Important variables for the function and longevity of such disc anthroplasty implants are clearly defined by the material properties of the components used for their production. Polyethylene (glycol) diacrylate-based hydrogels are powerful tools for uncovering basic cellular biology because they are considered biologically inert (“blank slate”) and their mechanical properties can be varied over a large series of moduli. In addition to, PEGDA hydrogels is an emergent scaffold for tissue engineering and Regenerative Medicine since polymerization can occur rapidly at room temperature and requires low exertion input, has high water contented, is flexible, and can be modified to include a variety of biological molecules. PEGDA hydrogels are easily customizable since ECM proteins and/or growth factors can be incorporated into a hydrogel and its elasticity can be modulated from 10- 100 kPa. The complex form of an intervertebral disc can be made with the help of rapid prototyping to serve as a medium in the spine. Stereolithography was chosen to construct the disc with desired quality and dimensions.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Jaiganesh V Dhileep Kumar J Girija Devi J


Stereolithography, Poly (ethylene glycol) diacrylate (PEGDA),Intervertebral disc, Spine, #

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version