alexa Abstract | Role of surfactant and pH in dissolution of curcumin

Indian Journal of Pharmaceutical Sciences
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Short Communication Open Access

Abstract

Curcumin is a phytoconstituent with wide range of biological activity. It is poorly soluble in water. In the present study a new dissolution medium was developed, as there is no validated dissolution method available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37°. Solubility data revealed that addition of surfactant may be suitable as a dissolution medium. The suitability of dissolution medium (0.5% sodium lauryl sulphate in water) relative to the other dissolution medium was evaluated. The selected dissolution media was used for the evaluation of curcumin tablets.

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Author(s): SMH Rahman TC Telny TK Ravi S Kuppusamy

Keywords

Curcumin, dissolution medium, sodium lauryl sulphate

 
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