alexa Abstract | Screening of phytochemical and antimicrobial activity from the leaves of Pleiospermium alatum (Wall. & Arn.) Swingle

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

The antimicrobial activity of Pleiospermium alatum leaves were extracted successively with different solvents viz., Petroleum ether, chloroform, ethyl acetate and methanol. Screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogenes, Enterococcus faecalis, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Vibrio cholerae. Candida albicans, Candida parapsilosis and Candida tropicalis by using disc diffusion method, the extent of the inhibitory zones, Minimum Inhibitory Concentration (MIC) Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were also determined. The methanol extract of P. alatum showed the highest antimicrobial activity against all the bacterial and fungal strains tested than the other extracts. The mean zones of inhibition produced by the extracts in agar diffusion assays against the tested bacterial strains ranged from 7.0 to 19.8 mm. The MIC values were between 125 and 250μg/ml, MBC values250 and 1000 μg/ml and MFC 250 and 1000 μg/ml values were recorded. Phytochemical analyses of different extracts of leaves P. alatum was analysed. The methanol extract of P. alatum leaves are showed the presence of strong phytochemicals viz., steroids, flavonoids, tannins, phenolic compounds and terpenoids than the other extracts. The highest mean of zone inhibition (19.8 mm) was observed in the methanol the extract of P. alatum against Staphylococcus aureus. These finding suggest that the methanol extract of Pleiospermium alatum can be used as a antimicrobial substance for the treatment of microbial infections.

To read the full article Peer-reviewed Article PDF image

Author(s): Umaiyambigai D and Saravanakumar K

Keywords

Antimicrobial activity, Pleiospermium alatum, MIC, MBC, MFC, phytochemical , antimicrobial

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords