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Medicinal plants are extensively used to cure various infectious diseases in human beings, hence S. nigrum, was investigated for its activity against the isolated pathogens from sputum samples. The study was designed to screen and characterize the bacteria isolated from the respiratory tract infected patients. Aqueous, ethanol and diethyl ether extract of S. nigrum was prepared; four different concentrations of each extract was taken to determine the antibacterial activity against the isolated bacteria. The ethanolic extract of S. nigrum showed highest antimicrobial activity in comparison to aqueous and diethyl ether extracts. Phytochemical analysis of the plant showed the presence alkaloids, terpenoids, flavonoids, saponins, steroids and phenols. Thus S. nigrum has antimicrobial activity and can be used clinically to find novel antibacterial compounds for respiratory tract pathogens.
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Author(s): M Rajathi D Modilal R Anandan R Sindhu and MN Logeshwari
Respiratory tract infections, Antibacterial activity, Phytochemical activity, S. nigrum, Secondary metabolites., Animal Physiology, Cell and molecular biology, Genetics, Biochemistry, Biotechnology, Bioinformatics, Microbiology, Immunology, Parasitology