alexa Abstract | Sero-Prevalence and Factors Associated with Toxoplasma Gondii Infection among Pregnant Women Attending Antenatal Care in the Referral Hospital in Tanzania: Cross Sectional Study

Annals of Clinical and Laboratory Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Background: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. It is estimated that more than one third of the global population is infected with this parasitic infection. Serological screening of pregnant women for the presence of T. gondii antibodies is not part of the antenatal care package in Tanzania. The current study assessed sero-prevalence and associated factors for T. gondii infection among pregnant women attending antenatal care clinic in KCMC referral Hospital.

Methods: Between April 26th to May 18th 2014 a total of 144 pregnant women attending KCMC for antenatal care were enrolled and screened for IgG and IgM antibodies against parasite T. gondii using lateral flow chromatography Assay which detects and differentiates IgM and IgG anti-T. gondii in human serum or plasma. Positive IgG results meaning, at some point in the life someone has been exposed to T. gondii and doesn’t mean the active infection.

Results: Of 144 expectant women investigated, 60 (41.7%) were seropositive for T. gondii-specific antibodies. Among sero-positive pregnant women 1 (1.7%) had anti-Toxoplasma IgM indicating acute infection. The risks of contracting T. gondii was less by nearly 50% among pregnant women 30-years-old and above compared with those below 30-years-old (Crude OR=0.45: 95% CI 0.23-088; p=0.2). There was no statistical evidence for the difference (p=0.059) among T. gondii positive women across different age groups. HIV infection was not statistically significant associated with T. gondii infection [adjusted OR 1.17: CI 0.42–3.24; p=0.764.

Conclusions: One third of pregnant women attended at antenatal clinic were seropositive for T. gondii at some point in their life which might increase neonatal complications. Due to complications related to Toxoplasmosis during pregnancy in   period: such miscarriage, chorioretinitis, hydrocephalus, cerebral calcification and fetal death. There is urgent need for screening during antenatal care.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Elichilia R Shao Stanley G Ndazana Wilfred Chacha Gileard Masenga Sonda Tolbert Dominic Mosha Emmanuel G Kifaro and Balthazar M Nyombi

Keywords

Toxoplasmosis, Trimester, Congenital, Hydrocephalus, Northern Tanzania, Gynecology Research, Clinical and Diagnosis, Zoonotic Hookworm

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords