alexa Abstract | Serum Biomarkers for Evaluating Portal Hypertension

Archives of Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article Open Access


Cirrhosis represents the final stage for wide variety of chronic liver diseases, regardless of its etiology, and the development of portal hypertension is responsible for the pathogenesis of most frequent and fatal complications of cirrhosis. It is of most importance to evaluate patients newly diagnosed with cirrhosis for the presence of clinically significant portal hypertension and associated complications, which could expose the patient to fatal conditions such as variceal bleeding. The most accurate method for evaluating the presence and severity of portal hypertension is the measurement of the hepatic venous pressure gradient, which in one hand provides us valuable prognostic information but on the other hand, it represents a problematic technique, because it is invasive, costly and not available in all centers. Several alternative noninvasive techniques have been proposed to assess portal hypertension, including serum biomarkers and imaging techniques. Various serum molecules have been investigated for their ability to predict the presence of portal hypertension, some of which have showed to either correlate with the hepatic venous pressure gradient or predict clinically significant portal hypertension. This chapter will focus on the potential role of multiple serum markers of portal hypertension that could be clinically applicate to predict the presence of clinically significant portal hypertension, to stratify patients with respect to the severity of portal hypertension, to predict lethal complications such as variceal bleeding, and to monitor disease progression or treatment response without exposing patients to the risks of repeated invasive assessment.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Saad Elias Barhoum Masad Assy Nimer


Hypertension, Cirrhosis, Patients, Emergency Medicine

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us