700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ ReadersThis Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Short Communication Open Access
A simple, specific, accurate and precise reverse phase high pressure liquid chromatographic method has been developed for the simultaneous determination of nimesulide and tizanidine from tablets. The sample was analyzed using methanol: water in the ratio of 65:35, pH adjusted to 4.15 with orthophosphoric acid on an octadecylsilane C18 column. The effluent was monitored at 1.4 ml/min flow rate using 307 nm as detecting wavelength. The linear dynamic ranges for nimesulide and tizanidine were 0.2-1.0 mg/ml and 10-50 mg/ml, respectively. Coefficients of correlation obtained for nimesulide and tizanidine were 0.998 and 0.996 - respectively.