alexa Abstract | Simultaneous spectrophotometric determination of atorvastatin calcium and amlodipine besylate in tablets

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access

Abstract

Two simple, accurate and precise methods for simultaneous estimation of atorvastatin calcium and amlodipine besylate in combined dosage form have been described. First method employs formation and solving of simultaneous equations using 245 nm and 363 nm as two analytical wavelengths. Second is dual wavelength method, which uses the difference of absorbance value at 259.9 nm and 354 nm for estimation of atorvastatin calcium and absorbance at 363 nm for amlodipine besylate. Fifty percent methanol was used as solvent, in which atorvastatin calcium and amlodipine besylate shows linearity in the range of 0-40 µg/ml and 0-20 µg/ml, respectively. Standard deviation was <1.5 in the assay of tablets. Methods were validated as per ICH norms and accuracy, precision, repeatability and robustness was found to be with in the acceptable limit.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): MR Khan Deepti Jain

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us