alexa Abstract | Simultaneous spectrophotometric estimation of hydrochlorothiazide and bisoprolol fumarate in combined dosage forms

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access


Rapid, precise, accurate, and specific ratiospectra derivative spectrophotometry and a simple UV spectrophotometry using simultaneous equation methods are developed for the simultaneous determination of bisoprolol fumarate and hydrochlorothiazide from combined pharmaceutical dosage forms. For ratiospectra derivative spectrophotometry, the amplitudes were measured at 202.6 nm for bisoprolol fumarate and the difference in amplitudes at 212.6 and 230 nm were measured for the determination of hydrochlorothiazide. In the simultaneous equation method, the signals were measured at 223 nm and 271.6 nm. Concentration of each drug was obtained by using the absorptivity values calculated for the drugs at two wavelengths, 223 and 271.6 nm. Commercial tablet formulations were successfully analyzed using the developed methods.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): R Sahu Vandana B Patel

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version