alexa Abstract | Simultaneous UV spectrophotometric estimation of ambroxol hydrochloride and levocetirizine dihydrochloride

Indian Journal of Pharmaceutical Sciences
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A novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of ambroxol hydrochloride and levocetirizine dihydrochloride. The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths 242 nm and 231 nm, the g max of ambroxol hydrochloride and levocetirizine dihydrochloride, respectively. Beer's law was obeyed in the concentration range 10-50 μg/ml and 8-24 μg/ml for ambroxol hydrochloride and levocetirizine dihydrochloride respectively. Results of the method were validated statistically and by recovery studies.

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Author(s): S Lakshmana Prabu AA Shirwaikar Annie Shirwaikar C Dinesh Kumar G Aravind Kumar


Ambroxol hydrochloride, levocetirizine dihydrochloride, l max, spectrophotometric method

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