alexa Abstract | Sleep Diary Approach of Sleep-Wake Cycle Disturbances in Cholera

Archives of Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Title: Sleep diary approach of sleep-wake cycle disturbances in cholera.

Background: Cholera is a pandemic caused by Vibrio cholerae (0:1 or 0:139 serotypes) that provokes a dramatic intestinal infection. Its endotoxin triggers abundant vomiting and diarrhoea leading to acute dehydration. Untreated, cholera is fatal in 25-30% of cases. Intensive rehydration and antibiotherapy reduces mortality toll to approximately 1%. Cholera reached sub-Saharan Africa in 1971 during the ongoing seventh pandemic. No sleep investigation having been reported previously in bedridden cholera patients, we analysed potential sleepwake disturbances during the 2013 epidemic at Pointe-Noire (Congo).

Methods and Findings: Nurses completed a sleep diary in 33 cholera patients, who stayed 3.4 ± 0.2 days in isolation at the hospital (Trial registration number: 2013-002-MSP-HGL-DAM). The 24-hour sleep-wake alternation was deregulated, sleep episodes occurring without day and night differences. In the daytime, sleep duration varied from Day 1 to Day 4 (ANOVA, P=0.0203), being shorter on Day 1 vs Day 2 (P= 0.0351) and longer on Day 2 vs Day 3 (P=0.0042). The number of sleep episodes was higher on Day 2 and Day 4 vs Day 1 (P=0.0055 and P=0.0399, respectively) and vs Day 3 (P=0.0007 and P=0.0084, respectively). At night, a time effect affected total sleep duration (P=0.0052), with a tendency for the number of sleep episodes (P=0.0671). Nocturnal sleep duration was longer on Day 1 and Day 2 vs Day 4 (P=0.0088 and P=0.0495, respectively). The number of sleep episodes was higher on Day 1 vs Day 4 (P=0.0487). During the 24 hours, a time effect was observed for total sleep duration (P=0.0001), with higher values on Day 2 vs Day 3 (P=0.0450).

Conclusions: Sleep-wake alterations were observed in cholera patients during the acute phase of the disease and were reversed during the rehydration process. The easy to use sleep diary may be thought of as a non-invasive tool for follow-up of cholera recovery and prognosis.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Donatien Moukassa Alain Buguet

Keywords

Cholera, Sleep-wake cycle alterations, Stress, Immune responses, Dehydration, General Medicine

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords